熊本大学大学院生命科学研究部 遺伝子機能応用学分野

Sato T, Sako Y, Sho M, Momohara M, Suico MA, Shuto T, Nishitoh H, Okiyoneda T, Kokame K, Kaneko M, Taura M, Miyata M, Chosa K,Koga T, Morino-Koga S, Wada I, Kai H.
STT3B-Dependent Posttranslational N-Glycosylation as a Surveillance System for Secretory Protein.
Mol Cell.2012 Jul 13;47(1):99-110. Epub 2012 May 17.

Komori H, Nishi K, Uehara N, Watanabe H, Shuto T, Suenaga A, Maruyama T, Otagiri M.
Characterization of hepatic cellular uptake of α1-acid glycoprotein (AGP), part 2: involvement of hemoglobin β-chain on plasma membranes in the uptake of human AGP by liver parenchymal cells. J. Pharm. Sci. 101(4):1607-15 (2012)

Komori H, Watanabe H, Shuto T, Kodama A, Maeda H, Watanabe K, Kai H, Otagiri M, Maruyama T.
α1-acid glycoprotein up-regulates CD163 via TLR4/CD14 pathway: possible protection against hemolysis-induced oxidative stress.
J Biol Chem. 2012 Aug.31.

Lee J, Komatsu K, Lee BC, Lim JH, Jono H, Xu H, Kai H, Zhang ZJ, Yan C, Li JD
Phosphodiesterase 4B Mediates Extracellular Signal-regulated Kinase-dependent Up-regulation of Mucin MUC5AC Protein by Streptococcus pneumoniae by Inhibiting cAMP-protein Kinase A-dependent MKP-1 Phosphatase Pathway.
J Biol Chem. 2012 Jun 29;287(27):22799-811. Epub 2012 May 18.

Morino-Koga S, Yano S, Kondo T, Shimauchi Y, Matsuyama S, Okamoto Y, Suico MA, Koga T, Sata T, Shuto T, Arima H, Wada I, Araki E, Kai H.
Insulin receptor activation through its accumulation in lipid rafts by mild electrical stress.
J Cell Physiol. 2012 Jun 27. doi: 10.1002/jcp.24149. [Epub ahead of print]

首藤 剛
新規ダニ誘発性掻痒自然発症モデルマウスの病態解析.
生化学.84(5),352-355,2012

Matsuno T, Kariya R, Yano S, Morino-Koga S, Taura M, Suico MA, Shimauchi Y, Matsuyama S, Okamoto Y, Shuto T, Kai H, Okada S.
Diethyldithiocarbamate induces apoptosis in HHV-8-infected primary effusion lymphoma cells via inhibition of the NF-κB pathway.
Int J Oncol. 2012 Apr;40(4):1071-8.

Mizunoe S, Shuto T, Suzuki S, Matsumoto C, Watanabe K, Ueno-Shuto K, Suico MA, Onuki K, Gruenert DC, Kai H.
Synergism Between Interleukin (IL)-17 and Toll-like Receptor 2 and 4 Signals to Induce IL-8 Expression in Cystic Fibrosis Airway Epithelial Cells.
J Pharmacol Sci. 2012 Apr;118(4):512-20. Epub 2012 Mar 29.

Koga T, Kai Y, Fukuda R, Morino-Koga S, Suico MA, Koyama K, Sato T, Shuto T, Kai H.
Mild electrical stimulation and heat shock ameliorates progressive proteinuria and renal inflammation in mouse model of Alport syndrome.
PLoS One 7(8):e43852.(2012)

Kondo T, Sasaki K, Matsuyama R, Morino-Koga S, Adachi H, Suico MA, Kawashima J, Motoshima H, Furukawa N, Kai H, Araki E.
Hyperthermia With Mild Electrical Stimulation Protects Pancreatic β-Cells From Cell Stresses and Apoptosis.
Diabetes. 2012 Apr;61(4):838-47. Epub 2012 Feb 23.

Taura M, Suico MA, Koyama K, Komatsu K, Miyakita R, Matsumoto C, Kudo E, Kariya R, Goto H, Kitajima S, Takahashi C, Shuto T, Nakao M, Okada S, Kai H.
Rb/E2F1 Regulates the Innate Immune Receptor Toll-Like Receptor 3 in Epithelial Cells.
Mol Cell Biol. 2012 Apr;32(8):1581-90. Epub 2012 Feb 6.