Paper 2019
遺伝性腎炎アルポート症候群の原因タンパク質Type IV collagen α3α4α5の三量体形成を標的とした治療戦略
大町 紘平，Suico Mary Ann，首藤 剛，甲斐 広文
Journal of Japanese Biochemical Society.2019 June;91(3):413-417.doi:10.14952/SEIKAGAKU.2019.910413
A cell-based high-throughput screening method to directly examine transthyretin amyloid fibril formation at neutral pH.
Ueda M, Okada M, Mizuguchi M, Kluve-Beckerman B, Kanenawa K, Isoguchi A, Misumi Y, Tasaki M, Ueda A, Kanai A, Sasaki R, Masuda T, Inoue Y, Nomura T, Shinriki S, Shuto T, Kai H, Yamashita T, Matsui H, Benson MD, Ando Y.
J Biol Chem. 2019 Jul 19;294(29):11259-11275. doi: 10.1074/jbc.RA119.007851. Epub 2019 Jun 5.
Auto-measure emphysematous parameters and pathophysiological gene expression profiles in experimental mouse models of acute and chronic obstructive pulmonary diseases
Nakashima R, Kamei S, Nohara H, Fujikawa H, Maruta K, Kawakami T, Eto Y, Takahashi N, Suico M.A., Takeo T, Nakagawa N, Kai H, Shuto T.
J Pharmacol Sci. 2019 140(2), 113-119 doi:10.1016/j.jphs.2019.01.011
Impact of hepatic HSP72 on insulin signaling
Kitano, S., Kondo, T., Matsuyama, R., Ono, K., Goto, R., Takaki, Y., Hanatani, S., Sakaguchi, M., Igata, M., Kawashima, J., Motoshima, H., Matsumura, T., Kai, H., Araki, E.
Am J Physiol Endocrinol Metab. 2019 Feb 1;316(2):E305-E318. doi: 10.1152/ajpendo.00215.2018.
Transthyretin Amyloid Fibril Disrupting Activities of Extracts and Fractions from Juglans mandshurica Maxim. var. cordiformis (Makino) Kitam.
Chaudhary N., Sasaki, R., Shuto, T., Watanabe, M., Kawahara, T., Suico, M.A., Yokoyama, T., Mizuguchi, M., Kai, H., Devkota, H.
Molecules. 2019 Jan 30;24(3). pii: E500. doi: 10.3390/molecules24030500.
Curcumin down-regulates toll-like receptor-2 gene expression and function in human cystic fibrosis bronchial epithelial cells.
Chaudhary N, Ueno-Shuto K, Ono T, Ohira Y, Watanabe K, Nasu A, Fujikawa H, Nakashima R, Takahashi N, Suico MA, Kai H, Shuto T
Biol Pharm Bull. 2019 42(3):489-495. doi: 10.1248/bpb.b18-00928.
Integrative expression analysis identifies a novel interplay between CFTR and linc-SUMF1-2 that involves CF-associated gene dysregulation
Kamei S, Maruta K, Fujikawa H, Nohara H, Ueno-Shuto K, Tasaki Y, Nakashima R, Kawakami T, Eto Y, Suico MA, Suzuki S, Gruenert DC, Li JD, Kai H, Shuto T.
Biochem Biophys Res Commun. 2019 Feb 5;509(2):521-528. doi: 10.1016/j.bbrc.2018.12.152. Epub 2018 Dec 28.
