Paper 2025
Melinjo-derived Gnetin C restores metabolic balance via dual adipose and hepatic effects in high-fat diet mice.
Kishimoto T, Nasu A, Uemura M, Kawano K, Ogasawara C, Fukuyama A, Nohara H, Nakashima R, Takahashi N, Fujiwara Y, Ikuta T, Suico MA, Kai H, Shuto T.
Sci Rep. 2025 Nov 25;15(1):41801. doi: 10.1038/s41598-025-25705-x.
PMID: 41290813
Dapagliflozin with losartan but not olmesartan has an add-on protective effect in experimental Alport syndrome.
Horizono J, Mizumoto K, Suico MA, Kaseda S, Sannomiya Y, Tsuhako H, Owaki A, Sato R, Shiraga M, Kato R, Kumabe R, Shuto T, Kai H.
J Pharmacol Sci. 2025 Dec;159(4):252-255. doi: 10.1016/j.jphs.2025.09.008. Epub 2025 Sep 20.
PMID: 41241435
Establishing a nanoluciferase-based assay as a high-throughput screening platform for therapeutics in congenital nephrotic syndrome.
Tsuhako H, Suico MA, Kojima H, Takahashi S, Tanigawa S, Kamura M, Sato R, Kato R, Owaki A, Nishinakamura R, Shuto T, Kai H.
J Pharmacol Sci. 2025 Dec;159(4):219-228. doi: 10.1016/j.jphs.2025.09.006. Epub 2025 Sep 20.
PMID: 41241432
Effect of 2-Hydroxypropyl-γ-cyclodextrin on Renal Inflammation in Alport Mouse Model.
Horizono J, Mizumoto K, Suico MA, Shirakawa A, Kaseda S, Sannomiya Y, Tsuhako H, Owaki A, Sato R, Shiraga M, Kato R, Kumabe R, Shuto T, Ishitsuka Y, Kai H.
Biol Pharm Bull. 2025;48(9):1456-1463. doi: 10.1248/bpb.b25-00417.
PMID: 41033979
Efficacy of Nrf2 activation in a proteinuric Alport syndrome mouse model.
Kaseda S, Horizono J, Sannomiya Y, Kuwazuru J, Suico MA, Sato R, Fukiya H, Sunamoto H, Ogi S, Matsushita T, Koyama Y, Owaki A, Tsuhako H, Shiraga M, Watanabe H, Nakano T, Davenport B, Nozu K, Yamamoto M, Shuto T, Tokunaga Y, Lennon R, Onuma K, Kai H.
Life Sci Alliance. 2025 Jun 17;8(8):e202503330. doi: 10.26508/lsa.202503330. Print 2025 Aug.
PMID: 40527586
Japanese black vinegar Kurozu promotes lifespan and healthspan extension in Caenorhabditis elegans
Fukushima Y, Kagami A, Sonoda H, Shimokawa K, Nishikawa S, Suico MA, Kai H,Miyazaki M, Torigoe K, Yoshinaga Y, Matsumoto Y, Shuto T.
JPharmacol Sci. 2025;157(4):233-241.doi:10.1016/j.jphs.2025.02.003
Pharmacokinetic Profiles of Melinjo Seed Extract Components in Rats.
Yamaga M, Kishimoto T, Tani H, Suico MA, Shuto T, Ikuta T.
ACS Food Sci Tech. 2025;5(2):653–658.doi:10.1021/acsfoodscitech.4c00803.
