熊本大学大学院生命科学研究部 遺伝子機能応用学分野

遺伝性腎炎アルポート症候群の原因タンパク質Type IV collagen α3α4α5の三量体形成を標的とした治療戦略

大町 紘平,Suico Mary Ann,首藤 剛,甲斐 広文
Journal of Japanese Biochemical Society.2019 June;91(3):413-417.doi:10.14952/SEIKAGAKU.2019.910413

Auto-measure emphysematous parameters and pathophysiological gene expression profiles in experimental mouse models of acute and chronic obstructive pulmonary diseases

Nakashima R, Kamei S, Nohara H, Fujikawa H, Maruta K, Kawakami T, Eto Y, Takahashi N, Suico, M.A., Takeo T, Nakagawa N, Kai H, Shuto T.
J Pharmacol Sci. 2019 Mar; 7: doi:10.1016/j.jphs.2019.01.011

Impact of hepatic HSP72 on insulin signaling

Kitano, S., Kondo, T., Matsuyama, R., Ono, K., Goto, R., Takaki, Y., Hanatani, S., Sakaguchi, M., Igata, M., Kawashima, J., Motoshima, H., Matsumura, T., Kai, H., Araki, E.
Am J Physiol Endocrinol Metab. 2019 Feb 1;316(2):E305-E318. doi: 10.1152/ajpendo.00215.2018.

Transthyretin Amyloid Fibril Disrupting Activities of Extracts and Fractions from Juglans mandshurica Maxim. var. cordiformis (Makino) Kitam.

Chaudhary N., Sasaki, R., Shuto, T., Watanabe, M., Kawahara, T., Suico, M.A., Yokoyama, T., Mizuguchi, M., Kai, H., Devkota, H.
Molecules. 2019 Jan 30;24(3). pii: E500. doi: 10.3390/molecules24030500.

Curcumin down-regulates toll-like receptor-2 gene expression and function in human cystic fibrosis bronchial epithelial cells.

Chaudhary N, Ueno-Shuto K, Ono T, Ohira Y, Watanabe K, Nasu A, Fujikawa H, Nakashima R, Takahashi N, Suico MA, Kai H, Shuto T
Biol Pharm Bull.2019 Jan 10. doi: 10.1248/bpb.b18-00928.

Integrative expression analysis identifies a novel interplay between CFTR and linc-SUMF1-2 that involves CF-associated gene dysregulation

Kamei S, Maruta K, Fujikawa H, Nohara H, Ueno-Shuto K, Tasaki Y, Nakashima R, Kawakami T, Eto Y, Suico MA, Suzuki S, Gruenert DC, Li JD, Kai H, Shuto T.
Biochem Biophys Res Commun. 2019 Feb 5;509(2):521-528. doi: 10.1016/j.bbrc.2018.12.152. Epub 2018 Dec 28.