ASCB 51st Annual Meeting （2011.12.3-7）Denver, Colorado, USA

"Lucidenic acids-rich extract from antlered from of Ganoderma lucidum enhances TNFα induction in THP-1 monocytic cells possibly via its modulation of MAP kinases p38 and JNK"
M. Sato, K. Watanabe, T. Shuto, S. Mizunoe, S. Suzuki, M. Ann Suico, T. Ikeda, H. Kai

"Mild electrical stimulation with heat shock ameliorates diabetic nephropathy."
Y. Okamoto, S. Morino-Koga, T. Koga, K. Omachi, M. Suico, T. Shuto, H. Kai

"Tsukushi differentially modulates TLR2- and TLR4-mediated signaling in murine macrophages "
K. Watanabe, T. Shuto, M. Sato, K. Onuki, M. Suico, K. Ohta, H. Kai

"Protective effects of p53 in a mouse model of progressive hereditary kidney disease Alport syndrome. "
R. Fukuda, K. Koyama, T. Koga, Y. Kai, M. A. Suico, T. Shuto, H. Kai

5th Young Investigators Symposium on Clinical Pharmaceutical Sciences（2011.11.26-27）Nagoya,Japan

"Camostat mesilate improves the mucus hypersecretory and emphysema-like phenotypes in airway-specific -epithelial Na+ channel-transgenic mice"
Tomomi Ono, Tsuyoshi Shuto, Chizuru Matsumoto, Yuki Sakaguchi, Shunsuke Kamei, Mary Ann Suico, Hirofumi Kai

"Mild electrical stimulation suppresses pro-inflammatory cytokines expression via inhibition of multiple signaling pathways "
Ihori Shitanda, Yuishiro Shimauchi, Saori Morino-Koga, Shuichiro Yano, Tomoaki Koga, Shingo Matsuyama, Mary Ann Suico, Tsuyoshi Shuto, Hirofumi Kai

"Evaluation of pulmonary phenotypes in low-mortality airway specific β-epithelial Na+ channel-transgenic mice by DNA microarray and invasive lung function measurement"
Yuki Sakaguchi, Tsuyoshi Shuto, Tomomi Ono, Chizuru Matsumoto, Takuya Sugahara, Shunsuke Kamei, Mary Ann Suico, Hirofumi Kai

The 27th International Kumamoto Medical Bioscience Symposium（2011.11.23）Kumamoto,Japan

【招待講演】
"Intracellular trafficking of amyloidogenic TTR and its therapeutic implications"
Hirofumi Kai

8th International Symposium on Familial Amyloidotic Polyneuropathy（2011.11.20-22）Kumamoto,Japan

"Posttranslational N-glycosylation regulates the quality control of transthyretin in the ER"
Takashi Sato, Yasuhiro Sako, Misato Sho, Mamiko Momohara, Hideki Nishitoh, Koichi Kokame, Masayuki Kaneko, Mary Ann Suico, Tsuyoshi Shuto, Tomoaki Koga, Saori Morino-Koga, Ikuo Wada, Hirofumi Kai

"Endoplasmic reticulum quality control regulates the fate of transthyretin variants in the cell"
Takashi Sato, Seiko Susuki, Mary Ann Suico, Masanori Miyata, Yukio Ando, Mineyuki Mizuguchi, Tsuyoshi Shuto, Hirofumi Kai

"The endoplasmic reticulum-associated degradation of transthyretin variants is negatively regulated by BiP in mammalian cells"
Takashi Sato, Seiko Susuki, Masanori Miyata, Mamiko Momohara, Mary Ann Suico, Tsuyoshi Shuto, Yukio Ando, Hirofumi Kai

"Role of the glutamic acid 54 residue in transthyretin stability and thyroxine binding"
Misato Sho, Masanori Miyata, Takashi Sato, Mineyuki Mizuguchi, Teruya Nakamura, Shinji Ikemizu, Yoshiaki Suwa, Hiroshi Morioka, Yukio Ando, Mary Ann Suico, Tsuyoshi Shuto, Yuriko Yamagata, Hirofumi Kai

"The crystal structure of the green tea polyphenol(-)-epigallocatechin gallate-transthyretin complex reveals a novel binding site distinct from the thyroxine binding site"
Misato Sho, Masanori Miyata, Takashi Sato, Teruya Nakmura, Shinji Ikemizu, Mami Chirifu, Mineyuki Mizuguchi, Yoshiaki Suwa, Hiroshi Morioka, Mary Ann Suico, Tsuyoshi Shuto, Yuriko Yamagata, Hirofumi Kai

25th Annual North American Cystic Fibrosis CONFERENCE（2011.11.3-5）Anaheim,California

"IL-17A primes cystic fibrosis airway epithelial cells to increase IL-8 expression in the presence of bacterial components."
S. Mizunoe ; S. Tuyoshi ; S. Suzuki ; C. Matsumoto ; K. Ueno-Shuto ; M. Suico ; B.J.Scholte ; D.C. Gruenert ; H . Kai

"Evaluation of pulmonary phenotypes in low-mortality airway-specific B-epithelial Na+ channel-transgenic mice by DNA microarray and invasive lung function measurements."
T. Ono ; C . Matsumoto ; Y . Sakaguchi ; T . Shuto ; T . Sugahara ; A . Mizuno ; M . Suico ; H . Kai

"Camostat mesilate improves the mucus hypersecretory and emphysema-like phenotypes in airway-specific B-epithelial Na+ channel-transgenic mice "
C . Matsumoto ; T . Ono ; Y . Sakaguchi ; T . Shuto ; T . Sugahara ; A . Mizuno ; M . Suico . H . Kai

5th International Congress on Stress Response in Biology and Medicine (2011.8.21-25) Quebec,Canada

"HRD1-dependent endoplasmic reticulum-associated degradation pathway is involved in the clearance of transthyretin variant."
Misato Sho, Takashi Sato, Yasuhiro Sako, Mamiko Momohara, Hideki Nishitoh, Masayuki Kaneko, Mary Ann Suico, Tsuyoshi Shuto and Hirofumi Kai

"Mild electrical stimulation suppresses fat accumulation and increases stress resistance via mitochondrial membrane potential-dependent activation of AMPK. "
Shingo Matsuyama , Shuichiro Yano , Saori Morino , Yuichiro Shimauchi, Mary Ann Suico, Tsuyoshi Shuto and Hirofumi Kai